The panel addresses the major components in the cycle of developing evidence-based policy and practice. The synthesis method, the core methodology to aggregate findings for evidence-based practice reviews, is defined and various types of syntheses will be compared. Using results from synthesis is the impetus for the Centers for Disease Control and Preventions system for synthesis and translational research, which is presented by those involved in developing the system. The translational process is further explored in a presentation of the Service to Science Academies (supported by the Substance Abuse and Mental Health Services Administration and the Center for Substance Abuse Prevention), an example of evaluation capacity building to increase the utilization of evidenced-based findings in the field and to bring practice into the evidence base. #synthesis #Translational #2010Conference #Alcohol,DrugAbuse,andMentalHealth #OrganizationalLearningandEvalCapacityBuilding #Evidence #EvaluationUse